Oral Glucose Tolerance for Project: SEC429N1 Test Description: The oral glucose tolerance test (oGTT) measures glucose levels following administration of a glucose challenge. A fasting blood sample is taken before the bolus of glucose is administered. Blood samples are collected every 30 minutes for 1 1/2 hours and tested for glucose by an Accu-Chek glucometer.

Level I Level I Data : Area Under Curve Mouse Label Genotype T-Zero T-30 T-60 T-90 Area SEC429N1-M-117 wt 64 277 193 116 16800.0 SEC429N1-M-145 wt 49 185 215 158 15105.0 SEC429N1-M-123 hom 51 183 143 97 12000.0 SEC429N1-M-139 hom 50 252 229 112 16860.0 SEC429N1-M-155 hom 55 248 286 177 19500.0 SEC429N1-M-171 hom 58 317 239 183 20295.0 Means: WT - 15952.5            HOM - 17163.75

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