Gene Summary for SEC632N1
Functional Category: signal transduction-ligand Cell Location: extracellular OST/GST: Original Accession #: Mouse Nucleotide Accession #: NM_054037 Human Nucleotide Accession #: NM_052863
Summary: No summary available.

Mouse Gene Sequence Information
	Nucleotide Reference:	NM_054037 ACCESSION:NM_054037 NID: gi 16905068 ref NM_054037.1 Mus musculus secretoglobin, family 3A, member 1 (Scgb3a1), transcript variant A, mRNA
	Protein Reference:	Q920D7 ACCESSION:Q920D7 NID: Mus musculus (Mouse). Uteroglobin-related protein 2 precursor (Cytokine HIN-1) (High in normal-1) (Secretoglobin family 3A member 1). MOUSESPTRNRDB
	Entrez Gene:	68662

Human Gene Sequence Information
	Nucleotide Reference:	NM_052863 Homo sapiens secretoglobin, family 3A, member 1 (SCGB3A1), mRNA
	Protein Reference:	Q96QR1 ACCESSION:Q96QR1 NID: Homo sapiens (Human). Uteroglobin-related protein 2 precursor (Cytokine HIN-1) (High in normal-1) (Secretoglobin family 3A member 1). HUMANSPTRNRDB
	Entrez Gene:	92304

Bibliographic References

Title Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Author[s] Reynolds Susan D, Reynolds Paul R, Pryhuber Gloria S, Finder Jonathan D, Stripp Barry R Journal Am J Respir Crit Care Med. 12/01/2002; 166:1498-509 Title HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Author[s] Krop I E, Sgroi D, Porter D A, Lunetta K L, LeVangie R, Seth P, Kaelin C M, Rhei E, Bosenberg M, Schnitt S, Marks J R, Pagon Z, Belina D, Razumovic J, Polyak K Journal Proc Natl Acad Sci U S A. 08/14/2001; 98:9796-801 Title Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. Author[s] Shigematsu Hisayuki, Suzuki Makoto, Takahashi Takao, Miyajima Kuniharu, Toyooka Shinichi, Shivapurkar Narayan, Tomlinson Gail E, Mastrangelo Domenico, Pass Harvey I, Brambilla Elisabeth, Sathyanarayana Ubaradka G, Czerniak Bogdan, Fujisawa Takehiko, Shimizu Nobuyoshi, Gazdar Adi F Journal Int J Cancer. 02/10/2005; 113:600-4 Title Down regulation of high in normal-1 (HIN-1) is a frequent event in stage I non-small cell lung cancer and correlates with poor clinical outcome. Author[s] Marchetti Antonio, Barassi Fabio, Martella Carla, Chella Antonio, Salvatore Simona, Castrataro Antonio, Mucilli Felice, Sacco Rocco, Buttitta Fiamma Journal Clin Cancer Res. 02/15/2004; 10:1338-43 Title DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. Author[s] Fackler Mary Jo, McVeigh Megan, Evron Ella, Garrett Elizabeth, Mehrotra Jyoti, Polyak Kornelia, Sukumar Saraswati, Argani Pedram Journal Int J Cancer. 12/20/2003; 107:970-5 Title Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. Author[s] Porter Dale, Lahti-Domenici Jaana, Torres-Arzayus Marisa, Chin Lynda, Polyak Kornelia Journal Mech Dev. 06/01/2002; 114:201-4

Mutation Information
Mutation Type:	Homologous Recombination (standard)
Description:	The gene consists of 4 exons, with the start codon located in exon 2 (NCBI accession NM_170727.1). Exons 1 through 4 were targeted.

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